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West Virginia Office of
Emergency Medical Services

350 Capitol Street
Room 425
Charleston WV, 25301

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OEMS Phone: (304) 558-3956
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Protocol 4902 - Patient Comfort; Addition of Ondansetron (Zofran)

While the information contained in this news article was current and accurate when we posted it, it may not necessarily represent current WVOEMS policy or procedure. If you have any questions, please contact our office at 304-558-3956.

Posted: Wednesday, September 10, 2008 8:17 AM

At a recent meeting of the WV EMS System's State Medical Policy and Care Committee, the addition of Ondansetron (Zofran) to Protocol 4902 - Patient Comfort was approved. The attached protocol reflects this change and is now approved for use by your staff after appropriate education occurs.

Ondansetron (Zofran) has proven to be an effective anti-nausea and anti-emetic edication with minimal significant side effects. Since nausea and vomiting are often ssociated with the 5-HT3 serotonin receptors in the brain (and possibly in other sites s well), 5-HT3 antagonists (like ondansetron) have been very effective in preventing or reating severe nausea and vomiting. The solution for injection is manufactured enerically as a 4 mg/2 ml single dose vial or 40 mg/20 ml multidose vial.

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